Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene lag1

By P. Hui. 2002

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Mammalian Ceramide Synthases (2010, background): “A truncated form of CerS2, which lacks 150 residues at the N-terminus, is also highly expressed in kidney and in liver, and was shown to inhibit colony formation of human hepatoma cells in vitro (49).”
Molecular Cloning, Characterisation and Tissue-specific Expression of Human LAG3, a Member of the Novel Lag1 Protein Family (2003, background): “However, the sequence of LASS2 is only 1977 bp (Pan et al., 2001).”
Manipulation of thyroid status and/or GH injection alters hepatic gene expression in the juvenile chicken (2007, background): “We discovered the chicken homolog of the yeast longevity-assurance gene (LASS2) , a T 3 -depressed gene in chickens, which seems to regulate hepatocyte growth in humans (Pan et al., 2001).”
Human MicroRNA Targets (2004, background): “…(1) CNOT7, a gene expressed in colorectal cell lines and primary tumors (Flanagan et al. 2003) (miR-15a); (2) LASS2, a tumor metastasis suppressor (Pan et al. 2001) (miR- 15b); (3) ING4, a homolog of the tumor suppressor p33 ING1b, which stimulates cell cycle arrest, repair, and apoptosis…”