High Serum Uric Acid as a Novel Risk Factor for Type 2 Diabetes

By Giuseppe Lippi, G. Targher, M. Montagnana, G. Salvagno, G. Guidi. Diabetes Care, 2008

672 citations recorded by the source corpus.

We read with interest the recent article by Dehghan et al. (1), who suggest that serum uric acid might be a strong and independent risk factor for diabetes. In particular, it was reported that the age- and sex-adjusted hazard ratios for diabetes were 1.30 for the 2nd quartile, 1.63 for the 3rd quartile, and 2.83 for the 4th quartile of serum uric acid, in comparison with the 1st quartile. To further investigate the association between uric acid and glucose homeostasis, we performed a retrospective analysis on the database of the Laboratory Information System of the Clinical Chemistry Laboratory at the Verona University Hospital to retrieve results …

Subfields: Epidemiology, Nephrology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/9f0bf189513a3f40cd46ebd18313d92b61e3aa84

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In Epidemiology

1. L. Tappy
2. K. Lê

Citations in the corpus

• Metabolic effects of fructose and the worldwide increase in obesity. (2010, background): “Although the mechanisms underlying the link between insulin resistance and hyperuricemia remain poorly defined, serum uric acid concentration appears to be a risk factor for the development of type 2 diabetes (61).”
• The Rotterdam Study: 2010 objectives and design update (2007, background): “The study showed that subjects with higher levels of serum uric acid have an increased risk of developing type 2 diabetes [40].”