Distinct dopamine neurons mediate reward signals for short- and long-term memories

By Nobuhiro Yamagata, Toshiharu Ichinose, Yoshinori Aso, P. Plaçais, Anja B. Friedrich, Richard J Sima, T. Préat, Gerald M. Rubin, Hiromu Tanimoto. 2014

233 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Ecology, Evolution, Behavior and Systematics, Genetics

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Citations in the corpus

Dopaminergic neurons write and update memories with cell-type-specific rules (2016, background): “…2010; Sejourne et al., 2011; Trannoy et al., 2011; Liu et al., 2012; Burke et al., 2012; Aso et al., 2012; Placais et al., 2013; Pai et al., 2013, Aso et al., 2014b; Lin et al., 2014; Bouzaiane et al., 2015; Ichinose et al., 2015; Yamagata et al., 2015; Owald et al., 2015; Huetteroth et al., 2015).”
Coordinated and Compartmentalized Neuromodulation Shapes Sensory Processing in Drosophila (2015, positive): “…activated the γ 4 and γ 5 DANs, in accord with their established role in driving the formation of appetitive olfactory associations (Liu et al., 2012; Yamagata et al., 2015; Waddell, 2013), we observed that sucrose ingestion also inhibited the γ 2 and γ 3 DANs (Figure 2B; Movie S1; Table S1).”
Dissecting neural pathways for forgetting in Drosophila olfactory aversive memory (2015, methodology): “This suggests that NP2397 labeled multiple subsets of PAM-DANs, which included but were not limited to PAM-β′1.”
The Drosophila Mushroom Body: From Architecture to Algorithm in a Learning Circuit. (2020, background): “There is evidence that, when presented with competing stimuli, flies suppress responses to the less relevant of those stimuli (van Swinderen 2007) and that dopamine and MBs are involved in these types of decisions (Zhang et al. 2007).”
Do the right thing: neural network mechanisms of memory formation, expression and update in Drosophila (2018, background): “Current Opinion in Neurobiology 2018, 49:51–58 different DANs [36,52] and that it is possible to artificially uncouple the taste and nutritious value by manipulating these neurons, or using a sweet but not nutritious sugar in an associative learning paradigm, then delivering nutritious food up to se”
A Higher Brain Circuit for Immediate Integration of Conflicting Sensory Information in Drosophila. (2015, background): “The effect of activation of these b02amp innervating PAM neurons was similar to the effect observed in two broader lines (MB042B and MB040B) that covered sugar-sensitive PAM neurons previously implicated in appetitive memory formation (Figure 2D, blue bars) [28].”
Neuronal mechanisms underlying innate and learned olfactory processing in Drosophila. (2019, background): “Many DANs respond 206 specifically to punishment (electric shock) or reward (sugar) [63], and blocking DANs 207 prevents memory formation [64-66], while artificial activation of DANs alone during odor 208 stimulus is sufficient to induce memory formation [67-73] (see Table 1).”
Distinct dopamine receptor pathways underlie the temporal sensitivity of associative learning (2019, background): “, 2009; Mao and Davis, 2009) and the protocerebral anterior medial (PAM) DANs conveying reward information (Burke et al., 2012; Liu et al., 2012; Yamagata et al., 2015).”
Reward signal in a recurrent circuit drives appetitive long-term memory formation (2015, unknown): “MB299B-GAL4 has strong expression in PAM-α1 (Aso et al., 2014a; Yamagata et al., 2015) (Figure 3B).”
Heterosynaptic plasticity underlies aversive olfactory learning in Drosophila (2015, unknown): “This matches well with the picture developed from recent behavioral studies indicating the different compartments are related to distinct motivational drives (Burke et al., 2012; Huetteroth et al., 2015; Krashes et al., 2009; Lin et al., 2014b; Liu et al., 2012; Musso et al., 2015; Yamagata et al., ”
A connectome of a learning and memory center in the adult Drosophila brain (2017, methodology): “The DANs which project to the a1 compartment, the ventral-most compartment of the vertical lobe (Figure 1), play a key role in the formation of appetitive long-term memory of nutritional foods (Yamagata et al., 2015).”