Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation.

By B. Salomon, J. Bluestone. Annual Review of Immunology, 2001

1,153 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/9ec82f47fe2f011a9daafe96531190a0553f3478

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. S. Rosenberg
2. Jie Yang
3. T. Gajewski
4. B. Fife
5. R. Sherry
6. U. Kammula
7. M. Hughes
8. S. Topalian

Citations in the corpus

• Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy (2005, background): “CD28 and CTLA-4 have MYPPPY motifs that are essential to bind B7-1 (CD80) and B7-2 (CD86).”
• The p110δ Isoform of Phosphoinositide 3-Kinase Controls Clonal Expansion and Differentiation of Th Cells1 (2006, result): “Consistent with previous results (28), IL-2 and IL-4 production in WT TCR transgenic cells were highly dependent on CD28 costimulation, as determined by their sensitivity to inhibition with CTLA4-Ig (Fig.”