An Expanded Eukaryotic Genetic Code

By J. Chin, T. Cropp, J. Christopher Anderson, Mridul Mukherji, Zhiwen Zhang, Peter G. Schultz. Science, 2003

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Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation (2014, background): “…into proteins in a residue-specific (Datta et al., 2002; Ngo and Tirrell, 2011; Tang et al., 2009) or site-specific manner (Carrico et al., 2007; Chin et al., 2003; Hudak et al., 2012; Hudak et al., 2011; Liu and Schultz, 2010; Wang et al., 2003a; Wu et al., 2009), and use in peptide tags that…”
Gelatinase-mediated migration and invasion of cancer cells. (2005, background): “In addition, the sitedirected amino acid analogue incorporation can also be directly applied to eukaryotic expression systems, including mammalian cells (Chin et al., 2003; Sakamoto et al., 2002).”
Handbook of ion channels (2015, methodology): “To incorporate unnatural amino acids (UAAs) into the protein of interest, a nonsense codon is introduced at the position of interest and the corresponding tRNA–UAA complex provided to be inserted into the position in question.”