Microencapsulation of a probiotic and prebiotic in alginate-chitosan capsules improves survival in simulated gastro-intestinal conditions.

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Chitosan Coating Applications in Probiotic Microencapsulation (2019, background): “bifidum [82,85] loaded in chitosan-coated alginate microspheres showed higher storage stability than free cell cultures.”
Encapsulation Technology to Protect Probiotic Bacteria (2012, background): “In another study, it was also observed that when quercetin was added together with probiotics, the microencapsulation yields and survival rates were lower than for the microorganism without quercetin [67].”
Co-encapsulation of probiotics with prebiotics on alginate matrix and its effect on viability in simulated gastric environment (2014, background): “Alginate, a biocompatible, cheap and non-toxic material to the body (Chavarri et al., 2010; Kermanshahi, Fooladi, & Peymanfar, 2010) is a natural anionic polysaccharide made up of D-mannuronic acid and glucuronic acid residues linked linearly by 1-4 glycosidic linkages (Annan, Borza, & Truelstrup Ha”