Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells.
By T. Ichimura, E. Asseldonk, B. Humphreys, L. Gunaratnam, Jeremy S. Duffield, Joseph V. Bonventre. Journal of Clinical Investigation, 2008
747 citations recorded by the source corpus.
Subfields: Immunology, Nephrology
View Paper: https://www.semanticscholar.org/paper/9da91f94de0e2daf1364739a667c34c75d4f6967
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In Immunology
In Nephrology
Citations in the corpus
- TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity (2010, background): “Before PtdSer was recognized as a TIM-1 ligand, a number of protein ligands had been proposed for TIM-1 including TIM-4 (43), TIM-1 (20, 49), TIM-3 (49), oxidized low density lipoprotein (48), and immunoglobulin-a heavy chain (50).”
- An Apoptotic 'Eat Me' Signal: Phosphatidylserine Exposure. (2015, background): “Tim1 is expressed in injured kidney cells and plasmacytoid dendritic cells, and binds PtdSer with an affinity similar to Tim4 [61,64].”
- Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury (2010, positive): “Immunofluorescence staining of the kidney was performed on paraffin sections as previously describe”