siRNA vs. shRNA: similarities and differences.

By D. Rao, John S. Vorhies, N. Senzer, J. Nemunaitis. Advanced Drug Delivery Reviews, 2009

672 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/9d141a7835e047e7ad501c101b52da580f5e3eda

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Leaf Huang
2. Ze Lu
3. Jie Wang
4. J. Au
5. Yunching Chen
6. M. Wientjes
7. Dong-Yu Gao

Citations in the corpus

• In vivo delivery of miRNAs for cancer therapy: Challenges and strategies (2014, background): “Moreover, the extrinsic therapeutic miRNA may compete with endogenous miRNA for the processing enzymes, which may lead to decreased expression of mature tumor suppressor miRNA [85,86].”
• Delivery of siRNA Therapeutics: Barriers and Carriers (2010, background): “siRNA may suppress off-targets due to partial nucleotide sequence match between the siRNA and off-target mRNA (21) and/or global degradation and inhibition of translation of mRNA caused by siRNA and its transfection agent (22, 23 ).”