Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
By M. Hellström, Li-Kun Phng, Jennifer J. Hofmann, Elisabet Wallgard, Leigh Coultas, P. Lindblom, Jackelyn A. Alva, A. Nilsson, L. Karlsson, N. Gaiano and 6 more. Nature, 2007
1,803 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/9d121f82c1c79e5bdcdbfab07eaef39e3083c940
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In Molecular Biology
- Alexey I. Nesvizhskii
- Dmitry Avtonomov
- Andy T. Kong
- W. Marston Linehan
- Eric E. Schadt
- G. Gurtner
- A. Robles
- Bing Zhang
Citations in the corpus
- The blood-brain barrier in health and chronic neurodegenerative disorders. (2008, positive): “Recent work has demonstrated that inhibition of Notch signaling with g-secretase inhibitors or genetic inactivation of Notch ligand delta-like 4 (Dll4) signaling promotes increased numbers of tip cells, which control vessel sprouting in the mouse retina (Hellstrom et al., 2007).”
- Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma (2019, background): “endothelial cell recruitment and tumor vasculature formation between the two subtypes (Birdsey et al., 2015; Cao, 2013; Chrzanowska-Wodnicka, 2013; Hellström et al., 2007; Zhou et al., 2018; Zhu et al., 2017).”
- Wound Healing: A Cellular Perspective. (2019, background): “The decision of whether endothelial cells become tip or stalk cells is regulated largely by the Notch pathway and its effectors, Delta-like 4 and Jagged1, which have been shown to control cell fate and patterning in several tissues, organisms, and developmental stages (179, 395).”