Monomethylarsonous acid (MMA(III)) is more toxic than arsenite in Chang human hepatocytes.
By J. Petrick, F. Ayala-Fierro, W. Cullen, D. E. Carter, H. Aposhian. Toxicology and Applied Pharmacology, 2000
691 citations recorded by the source corpus.
Subfields: Dermatology, Environmental Chemistry, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/9cc85a253cea424fc4ff697e362a43e35692bafa
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Citations in the corpus
- Arsenic in freshwater systems: Influence of eutrophication on occurrence, distribution, speciation, and bioaccumulation (2012, background): “Arsenite (AsIII) is usually more toxic than arsenate (AsV) 74 while dimethylarsinous acid (DMAAIII) and monomethylarsonous acid (MMAAIII) are more 75 toxic than their parent compounds (Mass et al., 2001; Petrick et al., 2000).”
- Mechanisms of arsenic biotransformation. (2002, background): “Arsenate reductase activity has been detected in human liver (Radabaugh and Aposhian, 2000).”
- Advances in metal-induced oxidative stress and human disease. (2011, background): “However, the results presented in the ast decade show that human cells are more sensitive to the cytooxic effects of MMAIII than arsenite (Petrick et al., 2000; Styblo t al., 2001) and that DMAIII is at least as cytotoxic as arsenite in everal human cell types (Styblo et al.”
- The Arsenic Methylation Cycle: How Microbial Communities Adapted Methylarsenicals for Use as Weapons in the Continuing War for Dominance (2020, background): “MAs(III) is more toxic than As(III) in Chang human hepatocytes (Petrick et al., 2000).”
- Aquatic arsenic: toxicity, speciation, transformations, and remediation. (2009, background): “Recent studies found that MMAIII and DMAIII are more acutely toxic and more genotoxic than their parent compounds (Mass et al., 2001; Petrick et al., 1993, 2000).”