Self-contained, fully integrated biochip for sample preparation, polymerase chain reaction amplification, and DNA microarray detection.

By Robin H. Liu, Jianing Yang, R. Lenigk, J. Bonanno, Piotr Grodzinski. Analytical Chemistry, 2004

661 citations recorded by the source corpus.

Subfields: Biomedical Engineering

View Paper: https://www.semanticscholar.org/paper/9bf2eaf1d92f5977a96ef6e19e96c382164d007a

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In Biomedical Engineering

1. Tza-Huei Wang
2. Samuel Yang
3. Shin Lin
4. Seungkyung Park
5. Yi Zhang
6. Wenli Ma
7. Jinliang Xu
8. Wenling Zheng

Citations in the corpus

• Advances in molecular technology and their impact on fisheries genetics (2008, background): “Other chips are currently in development that perform all steps of genetic analyses from DNA extraction to PCR amplification, potentially electrophoresis and data collection, thus covering the entire procedure from sample to data (Liu et al. 2004; Blazej et al. 2006; Kaigala et al. 2008).”
• Control and detection of chemical reactions in microfluidic systems (2006, methodology): “An elegant example of an integrated monolithic device for DNA amplification was reported by Liu et al. 81 .”
• Advances in Microfluidic PCR for Point-of-Care Infectious Disease Diagnostics (2011, background): “An integrated chip device that can detect E. coli from whole blood samples based on DNA hybridization and electrochemical sensing has been developed with a reported limit of detection of 103 cells/mL (Liu et al. , 2004).”
• PCR microfluidic devices for DNA amplification. (2006, methodology): “…Deshpande et al., 1999; Dunn et al., 2000; Friedman and Meldrum, 1998; Iordanov et al., 2003; Lagally et al., 2000, 2001a,b; Liao et al., 2005; Liu et al., 2003; Matsubara et al., 2005; Miao et al., 2003; Nagai et al., 2001a,b; Nakane et al., 2001; Poser et al., 1997; Stern et al., 2002;…”
• Magnetic bead handling on-chip: new opportunities for analytical applications (2004, background): “pumps, channels, chambers, heaters, and DNA microarray sensors was developed to perform DNA analysis of complex biological sample solutions (Liu et al. 2004).”