Synthetic circuits integrating logic and memory in living cells

By Piro Siuti, John Yazbek, Timothy K. Lu. Nature Biotechnology, 2013

543 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/9b0bf1cdd7fd027b97f389e727f579343ef2198d

Citations in the corpus

• Toehold Switches: De-Novo-Designed Regulators of Gene Expression (2014, unknown): “…(Friedland et al., 2009), oscillators (Elowitz and Leibler, 2000), toggle switches (Gardner et al., 2000), logic gates (Ausländer et al., 2012; Moon et al., 2012; Siuti et al., 2013; Win and Smolke, 2008), cell classifiers (Xie et al., 2011), and analog signal processors (Daniel et al., 2013).”
• Stem Cell Organoid Engineering (2016, unknown): “This platform can also be used for creating biosensors that record the history of cellular exposure to either individual or a sequence of environmental signals (Siuti et al., 2013).”
• A Comprehensive Survey of Recent Advancements in Molecular Communication (2014, unknown): “the receiver may be implemented by synthesizing logic gates and memory into cells as shown in [80], [81].”
• Genetic circuit design automation (2016, unknown): “This approach has led to digitallogic gates( 19 – 24 ),memorydevices( 25 – 29 ),analogcom-putation( 30 ),anddynamiccircuits(e.g.,timersand oscillators) ( 15 , 16 , 31 – 33 ).”