CLARITY for mapping the nervous system

By Kwanghun Chung, Karl Deisseroth. Nature Methods, 2013

715 citations recorded by the source corpus.

Subfields: Biophysics, Cellular and Molecular Neuroscience

View Paper: https://www.semanticscholar.org/paper/9b07b449f21ca08e6101188f62b9ce341c78df3d

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In Biophysics

In Cellular and Molecular Neuroscience

Citations in the corpus

Quicksilver: Fast Predictive Image Registration – a Deep Learning Approach (2017, background): “Even more dramatically, the microscopy field now routinely generates gigabytes of highresolution imaging data, for example, by 3D imaging via tissue clearing [4].”
Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits (2015, background): “Further development of high-throughput processing of these wholebrain datasets will be needed (Chung and Deisseroth, 2013; Kim et al., 2013, 2015) to fully capitalize on this opportunity for the rapid advancement of understanding structure-function relationships in the brain.”
Single-Cell Phenotyping within Transparent Intact Tissue Through Whole-Body Clearing (2014, methodology): “To image PACT-cleared tissue we have developed a refractive index matching solution (RIMS)—a custom economical recipe, with outcome similar to FocusClear (Chung et al., 2013; Moy et al., 2013; Tseng et al., 2009).”
Schizophrenia, Dopamine and the Striatum: From Biology to Symptoms (2019, background): “Recent methodological advances have further refined our understanding of corticostriatal architecture [9,10].”
On simplicity and complexity in the brave new world of large-scale neuroscience. (2015, background): “Experimental neuroscience is entering a golden age marked by the advent of remarkable new methods enabling us to record ever increasing numbers of neurons [1, 2, 3, 4, 5, 6], and measure brain connectivity at various levels of resolution [7, 8, 9, 10, 11, 12, 13, 14], sometimes measuring both connec”
Simple, scalable proteomic imaging for high-dimensional profiling of intact systems (2015, neutral): “Rapidly evolving tissue-clearing techniques may enable multiplexed labeling and imaging of intact samples using light microscopy (Chung et al., 2013; Chung and Deisseroth, 2013; Cell.”