Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

By J. V. Es, Toshiro Sato, M. Wetering, A. Lyubimova, Ann Nee, A. Gregorieff, Nobuo Sasaki, L. Zeinstra, M. V. D. Born, J. Korving and 4 more. Nature Cell Biology, 2012

783 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/9abccfecb7e03503ea6901c4423b3273a42608cc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Hans Clevers
2. M. V. D. van den Brink
3. Robert R. Jenq
4. R. Nusse
5. Elaine Fuchs
6. C. Blanpain
7. M. Resh
8. Jessica Rios-Esteves

In Oncology

1. Hans Clevers
2. Pengfei Lu

Citations in the corpus

• Interleukin-22 Promotes Intestinal Stem Cell-Mediated Epithelial Regeneration (2015, positive): “This was validated with a second independently established Lgr5 + ISC gene signature (GEO dataset GSE23672) 16 , while no significant changes were seen in a negative control Paneth cell gene signature (GEO dataset GSE39915) 17 (Extended Data Fig.”
• The intestinal crypt, a prototype stem cell compartment. (2013, background): “(G) Spi-B expression in microfold (M) cells. deletion of b-catenin (Fevr et al., 2007) or Tcf4 (van Es et al., 2012a) in adult mice.”