A new function for the γ -tubulin ring complex as a microtubule minus-end cap

By C. Wiese, Yixian Zheng. Nature Cell Biology, 2000

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Nature Reviews Molecular Cell Biology Microtubule nucleation by γ-tubulin complexes (2011, background): “In vitro , the γTuRC was shown to interact specifically with microtubule minus ends, at which it functions as a cap to prevent microtubule growth in the minus directio”
Phosphorylation of γ-Tubulin Regulates Microtubule Organization in Budding Yeast (2001, background): “An example of spindle displacement is shown al., 1999; Gunawardane et al., 2000; Zhang et al., 2000) in Figure 6B. At the start of the time lapse, an mtb (t or how -tubulin is positioned at the minus end of the 0:00) pulls the spindle toward the neck (t 0:22) and microtubule (Moritz et al., 2000; W”
Microtubule nucleation: γ-tubulin and beyond (2006, unknown): “⎫ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎬ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎪ ⎭ Jo ur na l o f C el l S ci en ce 4147Microtubule nucleation (Keating and Borisy, 2000; Moritz et al., 2000; Wiese and Zheng, 2000; Zhang et al., 2000; Zheng et al., 1995); and (4) all of the subunits of the TuRC are found at the centrosome.”
Spindle Dynamics and the Role of γ-Tubulin in Early Caenorhabditis elegans Embryos (2001, background): “Most evidence points to an exclusive association of g-TuRCs with minus ends (Keating and Borisy, 2000; Moritz et al., 2000; Wiese and Zheng, 2000).”