The distinction of metabolically ‘healthy’ from ‘unhealthy’ obese individuals

By M. Blüher. Current Opinion in Lipidology, 2010

611 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Epidemiology, Physiology

View Paper: https://www.semanticscholar.org/paper/99fea80ec8c1cb058e23d3081a170f53ce0429b3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. S. Grundy
2. A. Chait
3. Laura J. den Hartigh
4. I. Neeland

In Epidemiology

1. Jamal Naderi
2. M. Longo
3. C. Miele
4. Martin J. Blaser
5. G. A. Raciti
6. F. Beguinot
7. S. Fried
8. S. Grundy

In Physiology

1. Jamal Naderi
2. M. Longo
3. H. Smidt
4. C. Miele
5. James Kinross
6. Julian R. Marchesi
7. Martin J. Blaser
8. Ilseung Cho

Citations in the corpus

• Dysfunctional Adiposity and the Risk of Prediabetes and Type 2 Diabetes in Obese Adults (2012, background): “Our study may have implications for understanding differences between metabolically healthy and pathologic obesity.(39) The current findings suggest that a more metabolically healthy obesity phenotype is associated with decreased fat deposition in the abdominal viscera, increased lower body subcutan”
• Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences (2014, result): “Similar to DEXA, MRI showed increased body fat percentage in LDP-b male mice (Figures 1J–1M) and also identified LDP-induced ectopic fat deposition, including elevated total abdominal, visceral, and liver adiposity, which is linked with metabolic syndrome (Blüher, 2010; Rasouli et al., 2007).”
• The gut microbiota and host health: a new clinical frontier (2015, background): “29 Therefore, linking GI tract microbial composition directly and exclusively to obesity in humans will remain challenging due to the various confounding factors within the heterogeneous population.”
• Sex differences in human adipose tissues – the biology of pear shape (2012, background): “Certain individuals retain metabolic health despite being morbidly obese [77], while others develop disease at paradoxically normal adiposity levels [78].”
• Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease (2020, background): “Such individuals have been classified as having “metabolically healthy obesity” (MHO), and appear to be distinct from those with “metabolically unhealthy obesity” (MUHO) in that they remain insulin sensitive and do not have much adipose tissue inflammation or other features of the metabolic syndrome”
• Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications (2019, background): “Such healthy but overweight individuals are classified as “metabolically healthy obese” [50].”