Is Sleep Essential?
By Chiara Cirelli, Giulio Tononi. PLoS Biology, 2008
654 citations recorded by the source corpus.
No current hypothesis can explain why animals need to sleep. Yet, sleep is universal, tightly regulated, and cannot be deprived without deleterious consequences. This suggests that searching for a core function of sleep, particularly at the cellular level, is still a worthwhile exercise.
Subfields: Cognitive Neuroscience, Endocrine and Autonomic Systems
View Paper: https://www.semanticscholar.org/paper/993b693a7ec76be4488f6dea25741d2191f8fbc9
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cognitive Neuroscience
- Giulio Tononi
- Chiara Cirelli
- Jan Born
- Umberto Olcese
- S. Esser
- Björn H. Rasch
- V. Vyazovskiy
- György Buzsáki
In Endocrine and Autonomic Systems
Citations in the corpus
- Neuromodulation of brain states. (2012, neutral): “In particular, why is sleep so universal in the animal kingdom (Cirelli and Tononi, 2008), given that the loss of responsiveness to environmental stimuli makes the animal more vulnerable to predator attacks?”
- About sleep's role in memory. (2013, background): “, deprivation of sleep leads to subsequent longer sleep periods) (209).”
- Cortical firing and sleep homeostasis. (2009, background): “This homeostatic regulation is a main reason to think that sleep may serve an essential function for brain cells (Cirelli and Tononi, 2008).”
- Variation in sleep behaviour in free-living blue tits, Cyanistes caeruleus: effects of sex, age and environment (2010, background): “Sleep is a widespread behaviour in the animal kingdom, being found inmost if not all animals (Cirelli & Tononi 2008; Siegel 2008).”
- Sleep and synaptic renormalization: a computational study. (2010, background): “54 55 56 Keywords: sleep homeostasis, neural plasticity, STDP, downscaling, memory consolidation 57 58 59 60 61 62 63 64 65 Introduction 66 67 Sleep engages one third of our lives and is common to all animal species, yet its function remains 68 unknown (Cirelli & Tononi 2008).”