An autonomous molecular computer for logical control of gene expression

By Yaakov Benenson, Binyamin Gil, Uri Ben-Dor, Rivka Adar, Ehud Y. Shapiro. Nature, 2004

809 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/987d0dcaca80057764dda5c41727a6f344475506

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Georg Seelig
2. David Y. Zhang
3. S. Mayor
4. Jeannette M. Wing
5. Mark Coddington
6. Sze Yee Lye
7. Joyce Hwee Ling Koh

Citations in the corpus

• A DNA nanomachine that maps spatial and temporal pH changes inside living cells. (2009, background): “They can be used as sensors, motors or for logical analysis of gene expression in vitro”
• Dynamic DNA nanotechnology using strand-displacement reactions. (2011, background): “where the outcome (the release of an antisense drug mimic) was dependent on the absence or presence of specific inputs (ssDNA with sequence analogous to diagnostically relevant mRNA”
• Computational thinking and thinking about computing (2008, methodology): “Bio is here: Adleman (1994) solved the seven-point Hamiltonian path problem with DNA computing; Benenson et al. (2004) described in Nature the construction of a DNA computer.”
• Aptamers as therapeutics (2010, methodology): “In the future, it is possible that aptamers will use methods associated with nucleic acid computation to act as circulating circuitry networks with combined diagnostic and therapeutic capabilities 111 .”