Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases.

By Robert A. Waterland, R. Jirtle. Nutrition (Burbank, Los Angeles County, Calif.), 2004

808 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/981441dec8b0d407fef95555699127180043f97c

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Citations in the corpus

Epigenetics: Embedded bodies and the molecularisation of biography and milieu (2011, background): “…and Randy Jirtle at Duke University, Durham, NC, were able to show that feeding a diet rich in methyl-donor nutrients to agouti mouse dams for 2 weeks before mating is able to increase methylation at a particular DNA locus in the offspring influencing coat colour (Waterland and Jirtle, 2003, 2004).”
Etiologic Subtypes of Attention-Deficit/Hyperactivity Disorder: Brain Imaging, Molecular Genetic and Environmental Factors and the Dopamine Hypothesis (2007, background): “…likely would reflect either the direct action of an environmental toxicant or an indirect environmental effect of factors such as maternal diet (see Waterland & Jirtle, 2004; Dolinoy et al., 2006) or mother-child interactions (see Meaney & Szyf, 2005; Weaver et al., 2005) that can produce profound…”
Maternal Genistein Alters Coat Color and Protects Avy Mouse Offspring from Obesity by Modifying the Fetal Epigenome (2006, background): “This finding is consistent with methylation status of a single CpG in the glucocorticoid receptor gene promoter principally mediating the effect of maternal caregiving behavior on long-term stress responsiveness in rats (Weaver et al. 2004).”
Child health, developmental plasticity, and epigenetic programming. (2011, background): “Diet, hormones, and social and lifestyle factors (all of which will be discussed in this section) have all been shown to influence the epigenotype and may exert profound effects on many aspects of child and adult health and disease susceptibility in later life (62, 167, 416).”
Epigenetics and the embodiment of race: Developmental origins of US racial disparities in cardiovascular health (2009, background): “…environmental factors can modify epigenetic processes, thereby affecting epigenetic marks and downstream patterns of gene expression in specific cells and cell lineages (Gluckman et al., 2007a,b; Ho and Tang, 2007; Jirtle and Skinner, 2007; Waterland and Jirtle, 2004; Waterland and Michels, 2007).”
Epigenetic mechanisms that underpin metabolic and cardiovascular diseases (2009, background): “In this strain of mice, maternal deficiency of methyl donors and cofactors (such as folate) results in agouti promoter hypomethylation, increased prevalence of obesity, and cancer, and yellow coat color in the offspring”
Board-invited review: intrauterine growth retardation: implications for the animal sciences. (2006, neutral): “, stable alterations of gene expression through covalent modifications of DNA and core histones) in early embryos may be carried forward to subsequent developmental stages (Waterland and Jirtle, 2004).”