Sedentary time and cardio-metabolic biomarkers in US adults: NHANES 2003-06.

By G. Healy, C. Matthews, David W. Dunstan, E. Winkler, N. Owen. European Heart Journal, 2011

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Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis (2012, background): “Objective measures have demonstrated that the average adult spends 50–60% of their day in sedentary pursuits [2].”
Breaking Up Prolonged Sitting Reduces Postprandial Glucose and Insulin Responses (2012, background): “National Health and Nutrition Examination Survey (NHANES) and the 2004–2005 Australian Diabetes, Obesity and Lifestyle (AusDiab) study showed that objectively measured total sedentary time was detrimentally associated with cardiometabolic risk markers (3,4).”
Association of moderate to vigorous physical activity and sedentary time with cardiometabolic risk factors in children and adolescents (2012, neutral): “Boys were significantly more active than girls and spent about 55% more of average daytime in MVPA.”
Daily physical activity assessment with accelerometers: new insights and validation studies (2013, background): “The interest in identifying postures and activity types may be partly inducted by literature showing the health risk of sedentary behaviour, independent of the physical activity level (3,4,41).”