A Genetic Switch, Phage Lambda Revisited

By M. Ptashne. 2004

545 citations recorded by the source corpus.

How researchers see this paper

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Cellular Decision-Making and Biological Noise: From Microbes to Mammals (2011, background): “A particularly well-studied virus is bacteriophage lambda (Ptashne, 2004), which preys on the bacterium Escherichia coli”
The Epidemiology and Evolution of Symbionts with Mixed-Mode Transmission (2013, background): “This genetic switch can evolve quickly in response to selection and depends on the host’s genetic background (Ptashne 2004, Refardt & Rainey 2010).”
Nonequilibrium physics in biology (2019, background): “Phage lambda is a bacterial virus that infects the bacterium Escherichia coli (Balázsi and Collins, 2011; Ptashne, 2004b).”
The many faces of the helix-turn-helix domain: transcription regulation and beyond. (2005, background): “The affinities of the specific transcription factors for their target sequences on DNA were often found to be dependent on their interaction with low-molecular weight compounds (effectors), which bound to them, or phosphorylation and other post-transcriptional modifications [1].”