Bone tissue engineering: A review in bone biomimetics and drug delivery strategies

By Joshua R. Porter, Timothy T. Ruckh, K. Popat. Biotechnology progress (Print), 2009

756 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review (2011, background): “, growth factors, such as bone morphogenetic proteins (BMPs) and vascular endothelial growth factors (VEGFs)) [7,12,13].”
Bone substitutes in orthopaedic surgery: from basic science to clinical practice (2014, background): “Although local delivery of antibiotics has a very promising outlook, there remains a number of challenges (such as antibiotic stability within the scaffold and antibiotic deactivation during fabrication), which need to be addressed before clinical trials can begin [170].”
Natural Polymeric Scaffolds in Bone Regeneration (2020, background): “These principles consist in numerous strategies including gene therapy, drug and growth factor delivery, stem cell transplantation, and engineering of acellular scaffolds (Porter et al., 2009).”
Inflammation, Fracture and Bone Repair (2016, background): “Upon bone injury, macrophages release various cytokines, chemokines, and growth factors to recruit additional inflammatory cells, promote neovascularization, direct MSC migration and differentiation, and mediate remodeling [6,87,88].”
Collagen for bone tissue regeneration. (2012, background): “ment to exploit the natural biological response to tissue damage, and incorporating engineering and life science principles [45,46].”