Crystal structure of ATF‐2/c‐Jun and IRF‐3 bound to the interferon‐β enhancer

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Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. (2008, methodology): “Although the proposed model for the IFN-b enhanceasome features HMGI(Y) as a structural component, NF-kB, IRF3, and c-jun/ATF-2 can each form a stable structure with the promoter without HMGI(Y) (Berkowitz et al., 2002; Panne et al., 2004).”
Functional specificity of a Hox protein mediated by the recognition of minor groove structure. (2007, unknown): “For example, an Arg of phage 434 repressor inserts into the minor groove of its operator (Aggarwal et al., 1988), and a His in the DNA-binding domains of interferon regulatory factors (IRFs) inserts into a compressed minor groove (Escalante et al., 1998; Fujii et al., 1999; Panne et al., 2004).”
Epigenetic reprogramming and induced pluripotency (2009, background): “Protein-protein interactions between these transcription factors could increase the affinity of the proteins for adjacent recognition sites (Chen et al., 1998) or DNA conformations generated by the binding of one transcription factor could favor the binding of another (Panne et al., 2004).”