Collapse of a fish population after exposure to a synthetic estrogen

By K. Kidd, P. Blanchfield, K. Mills, V. Palace, R. Evans, J. Lazorchak, R. Flick. Proceedings of the National Academy of Sciences of the United States of America, 2007

2,114 citations recorded by the source corpus.

Subfields: Nature and Landscape Conservation, Physiology, Pollution

View Paper: https://www.semanticscholar.org/paper/9640c0b65d6716bfad9287736f2a4dbb96100cef

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Citations in the corpus

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment (2010, background): “[55] found that EE2 concentrations in the range of approximately 2 to 8 ng/L (over three years) resulted in collapse of a native fathead minnow population in a whole-lake dosing study.”
Global Water Pollution and Human Health (2010, background): “The active ingredient of the contraceptive pill [17α-ethinylestradiol (EE2)] and to a lesser extent industrial chemicals, such as alkylphenols or bisphenol A, were recognized to be able to cause “feminization” of fishes in exposed populations.”
Emerging threats and persistent conservation challenges for freshwater biodiversity (2018, background): “Across taxa, ﬁshes are most susceptible to the natural and synthetic hormones present in municipal efﬂuents, with effects ranging from the production of vitellogenin and development of intersex in males (Jobling et al. , 2002) to reduced abundances (Kidd et al. , 2007).”
Ecotoxicogenomics: Emerging Technologies for Emerging Contaminants 1 (2009, background): “The synthetic steroid ethynylestradiol (EE2) is an example of a well-studied pharmaceutical, shown to cause sublethal effects in fathead minnow leading to population decline at very low concentrations (Kidd et al., 2007).”
Environmental impact of estrogens on human, animal and plant life: A critical review. (2017, background): “…feminizemale fish e.g. reduce testes size (Arnold et al., 2014; Tetreault et al., 2011), affect reproductive fitness (Rose et al., 2013), lower sperm count, induce the production of vitellogenin (VTG) (Kidd et al., 2007) and alter other reproductive characteristics (Van Donk et al., 2016).”
An environmental oestrogen disrupts fish population dynamics through direct and transgenerational effects on survival and fecundity (2014, background): “Histological evidence suggested that observed declines in fathead minnow Pimephales promelas Rafinesque abundance were at least partly due to reproductive disruption (Kidd et al. 2007).”
Pharmaceuticals in the environment—Global occurrences and perspectives (2016, background): “At concentrations of 5 ng/L to 6 ng/L EE2 has been demonstrated to cause population collapse of fathead minnow (Pimephales promelas) as a result of feminization ofmale fish in a Canadian whole-lake experiment [8].”