Principles of Selective Ion Transport in Channels and Pumps

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CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures (2012, background): “by their size, shape and amino acid composition and can be efficiently modified by protein engineering [4,15,23–30].”
Structure of a bacterial multidrug ABC transporter (2006, background): “Moreover, this result would other- wise deviate from the proximal substrate arrangements that are found in other ion channel and ion transporter proteins (Zhou and MacKinnon, 2003; Gouaux and Mackinnon, 2005; Lobet and Dutzler, 2006; Shi et al, 2006).”
Protein Modelling: What Happened to the “Protein Structure Gap”? (2013, neutral): “Prominent examples include pharmacologically highly relevant drug targets such as GPCRs (Kobilka and Schertler, 2008), drug efflux transporters (Aller et al., 2009; Nakashima et al., 2013), or ion channels (Gouaux and Mackinnon, 2005).”
The role of functional traits and trade-offs in structuring phytoplankton communities: scaling from cellular to ecosystem level. (2007, background): “…ammonium, phosphate, iron, molybdenum, etc.) and carbon, it is possible that there may be a limited surface area available for an uptake of a particular ion, as only a part of cell surface is occupied by active uptake sites (Button 1998) and those sites are ion-specific (Gouaux & MacKinnon 2005).”