Directed evolution of industrial enzymes: an update.

By J. Cherry, A. Fidantsef. Current Opinion in Biotechnology, 2003

770 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Biotechnology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/94cfdb33cada523cb949ff835c69331e018eaf2e

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Citations in the corpus

Application of Central Composite Design Based Response Surface Methodology in Parameter Optimization and on Cellulase Production Using Agricultural Waste (2010, background): “The major barrier for this expansion is the current cost of cellulases in biomass saccharification [6].”
RESEARCH: Development of a mature fungal technology and production platform for industrial enzymes based on a Myceliophthora thermophila isolate, previously known as Chrysosporium lucknowense C1 (2011, neutral): “18”
Improving Enzymes for Biomass Conversion: A Basic Research Perspective (2010, background): “These include screening new organisms (mainly fungi) for superior versions of current enzymes and for enzymes that act synergistically with existing commercial enzymes, continued strain improvement by conventional and molecular mutagenesis, enzyme improvement by protein engineering and directed evol”
Outlook for cellulase improvement: screening and selection strategies. (2006, background): “Currently, most commercial cellulases (including βglucosidase) are produced by Trichoderma species and Aspergillus species (Cherry and Fidantsef, 2003; Esterbauer et al., 1991; Kirk et al., 2002).”
Native and Biotechnologically Engineered Plant Proteases with Industrial Applications (2011, background): “Detergent proteases represent the single largest volume of enzymes sold for industrial use, accounting for as much as 35% of the total industrial enzyme market (Cherry and Fidantsef 2003).”
Enzyme immobilization: an update (2013, background): “Furthermore, the attachment of an enzyme to a solid support can increase its resistance to various environmental changes such as pH or temperature [19].”
Characterization of extracellular cellulose-degrading enzymes from Bacillus thuringiensis strains (2012, background): “…cotton softening and denim finishing in the textile industry, colour care, cleaning, and anti-deposition in the detergent market; mashing in the food industry; and deinking, drainage improvement, and fiber modification in the pulp and paper industries (Kirk et al. 2002; Cherry and Fidantsef, 2003).”
Microbial Enzymes: Tools for Biotechnological Processes (2014, background): “Proteins from directed evolution work were already on the market in 2000 [85,86].”