Developing a new resource for drug discovery: marine actinomycete bacteria
By W. Fenical, P. Jensen. Nature Chemical Biology, 2006
793 citations recorded by the source corpus.
Subfields: Biotechnology, Molecular Biology, Pharmacology
View Paper: https://www.semanticscholar.org/paper/93ec6b2c3acd706de07207f7fed72d4ff85c0c38
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Citations in the corpus
- Marine Streptomyces as a novel source of bioactive substances (2010, background): “Recently, the rate of discovery of new metabolites from terrestrial actinomycetes has decreased, whereas the rate of re-isolation of known compounds has increased (Fenical et al. 1999; Fenical and Jensen 2006 ).”
- Screening of marine Streptomyces spp. for potential use as probiotics in aquaculture (2010, background): “Marine-derived Streptomyces have been studied for isolation of several novel secondary metabolites (Fenical and Jensen, 2006; Das et al., 2006a).”
- An Overview on Marine Sponge-Symbiotic Bacteria as Unexhausted Sources for Natural Product Discovery (2017, background): “The marine environment in particular has attracted much attention as a source of natural product discovery due to its vast biodiversity, the variety of environmental conditions and natural compound production by marine plants, invertebrates, and their microbial communities [2].”
- Natural products in drug discovery. (2008, methodology): “For example, salinosporamide A (Fig. 2) from Salinospora tropica potently inhibits the 20S proteasome and has anti-cancer activity in experimental models [ 18 ]; it is undergoing clinical trials.”
- Lessons from the past and charting the future of marine natural products drug discovery and chemical biology (2012, background): “From another perspective, while Actinomycetes and Myxobacteria are the richest terrestrial groups of bacteria in terms of number and diversity of natural product structures, these microbes were largely unrecognized in the world’s oceans until recently, and exploration of the extent and diversity of ”
- Screening of marine actinomycetes isolated from the Bay of Bengal, India for antimicrobial activity and industrial enzymes (2009, neutral): “2005; Fenical and Jensen 2006; Ramesh et al. 2006, 2009).”