Mammalian zinc transporters: nutritional and physiologic regulation.

By Louis A. Lichten, R. Cousins. Annual review of nutrition, 2009

748 citations recorded by the source corpus.

Subfields: Health, Toxicology and Mutagenesis, Hematology, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/93e78701bbb5cae680b7d3c2beed81d992da6eae

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Health, Toxicology and Mutagenesis

1. C. Brauner
2. A. Farrell
3. K. Młyniec
4. L. Rink
5. Taiho Kambe
6. C. Wood
7. Gabriela Wyszogrodzka
8. M. Olbert

In Hematology

1. K. Młyniec
2. L. Rink
3. Taiho Kambe
4. C. Wood
5. C. Brauner
6. A. Farrell
7. Gabriela Wyszogrodzka
8. M. Olbert

In Nutrition and Dietetics

1. L. Rink
2. K. Młyniec
3. H. Haase
4. Taiho Kambe
5. C. Wood
6. C. Brauner
7. A. Farrell
8. Gabriela Wyszogrodzka

Citations in the corpus

• Zinc biochemistry: from a single zinc enzyme to a key element of life. (2013, background): “Together these transporters control cellular zinc and its traffic through the plasma membrane and between cytosol and various cellular compartments (35,36).”
• The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism. (2015, methodology): “ZIP transporters function by replenishing cytosolic zinc from the extracellular space and the lumens of intracellular compartments (184, 189, 239) (FIGURES 4 AND 6A).”
• The Essential Toxin: Impact of Zinc on Human Health (2010, background): “The cellular homeostasis of zinc is mediated by two protein families; the zinc-importer (Zip; Zrt-, Irt-like proteins) family, containing 14 proteins that transport zinc into the cytosol, and the zinc transporter (ZnT) family, comprising 10 proteins transporting zinc out of the cytosol [10].”
• Zinc and human health: an update (2011, neutral): “…homeostasis of zinc is mediated by two protein families; the zinc-importer (Zip; Zrt-, Irt-like proteins) family, containing proteins that transport zinc into the cytosol, and the zinc transporter (ZnT) family, comprising proteins transporting zinc out of the cytosol (Lichten and Cousins 2009).”
• Ion Channels in Innate and Adaptive Immunity (2015, background): “The 14 ZIP transporters are located either in the PM or in the membrane of intracellular organelles, where they function to increase intracellular [Zn2+] by mediating Zn2+ influx or release, respectively (87).”
• Antioxidant and anti-inflammatory effects of zinc. Zinc-dependent NF-κB signaling (2017, background): “It was recently suggested that this is the mechanism for NF-jB inhibition by Zn2? that has been imported by ZIP8 into monocytes, macrophages, and lung epithelia during an infection (Liu et al. 2013).”
• Homeostasis and toxicology of essential metals (2012, background): “In contrast to the Znt family, which typically transport Zn away from the cytosol, all Zip paralogues appear to transport Zn into the cytosol, at least during normal physiological conditions (Hogstrand et al., 2009; Lichten and Cousins, 2009; Hershfinkel et al., 2010).”