Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications.

By C. Lastra, I. Villegas. Biochemical Society Transactions, 2007

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Potential Adverse Effects of Resveratrol: A Literature Review (2020, background): “Whenever RE acts as a pro-oxidant molecule in vitro, it can cause DNA damage and reduce several DNA repair pathways, which can activate cytotoxic and apoptotic pathways [104,105].”
Anti-Inflammatory Action and Mechanisms of Resveratrol (2021, background): “Introduction In 1976, resveratrol (3,4′,5-trihy- droxystilbene) was thought to be just a phytoalexin [1], one of the polyphenolic compounds produced by plants in response to environmental stress [2].”
Oxidative Stress, Prooxidants, and Antioxidants: The Interplay (2014, background): “Red wines also have a high content of phenolic substances including catechin and resveratrol [177], which are responsible for the antioxidant action, anti-inflammatory, antiatherogenic property, oestrogenic growth-promoting effect, and immunomodulation.”
Resveratrol: A Double-Edged Sword in Health Benefits (2018, background): “However, some studies have documented that it may behave as a pro-oxidizing agent [112]; thus, paradoxically, it may also have implication in pathology of several diseases.”