Liposome application: problems and prospects

By Y. Barenholz. 2001

596 citations recorded by the source corpus.

Subfields: Biomaterials, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/93313dd3552ef9d332cbf16c22bc09ce0ca7354b

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In Biomaterials

In Molecular Biology

Citations in the corpus

Nano-niosomes as nanoscale drug delivery systems: an illustrated review. (2014, background): “[67]).”
Liposomal Formulations in Clinical Use: An Updated Review (2017, methodology): “A high and stable drug/lipid ratio was obtained through the remote loading approach (Figure 5) (first developed by Barenholz [3]) by a transmembrane gradient of ammonium sulphate: [(NH4)2SO4] liposome >> [(NH4)2SO4] medium that serves as a driving force for the efficient and stable loading of amphip”
Doxil®--the first FDA-approved nano-drug: lessons learned. (2012, methodology): “We in Jerusalem used another remote loading approach, which is based on a transmembrane gradient of ammonium sulfate: [(NH4)2 SO4]liposome≫ [(NH4)2SO4]medium that acts as the driving force for the efficient and stable remote loading of amphipathic weak bases into preformed nano-liposomes [20,34,48,5”
Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems (2013, background): “To prevent initial drug leakage the lipid bilayer composition itself is altered, in conjunction with protocol changes to drug loading to stabilise the liposome’s ability to contain the drug effectively.([74,75]) Liposomes were soon coated with polyethylene glycol (PEG) to prolong circulation time.”
Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface. (2013, unknown): “While it is clear that nanoparticle size and shape are key factors for uptake 15-17 , current targeting strategies also involve conjugation of biofunctional moieties to nanoparticles in an effort to determine the biological outcomes 1,2,9,12,18-20 .”
Nanomedicine: current status and future prospects (2005, background): “type and the encapsulation method (119).”