Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
By Yuting Ma, Sandy Adjemian, S. Mattarollo, T. Yamazaki, L. Aymeric, H. Yang, João Paulo Portela Catani, D. Hannani, Hélène Duret, Kim Steegh and 17 more. Immunity, 2013
652 citations recorded by the source corpus.
Subfields: Immunology, Oncology
View Paper: https://www.semanticscholar.org/paper/9293dbf6e26011a58c7b6b275f1376cb858fa723
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In Oncology
Citations in the corpus
- Dendritic Cells and Cancer Immunity (2016, background): “For example, immune responses induced by anthracyclines or vaccines containing the toll-like receptor 7 (TLR7) agonist R848 provide protection in Batf3-deficient mice [24, 25].”
- Roles of the immune system in cancer: from tumor initiation to metastatic progression (2018, background): “…immune responses, ATP and damage signals released by necrotic cells induce the recruitment of myeloid cells; this is followed by local differentiation to CD11c + CD11b + Ly6C hi DCs that efficiently engulf tumor antigens in situ and prime the anti-tumor effector T-cell response (Ma et al. 2013).”
- Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents. (2015, background): “In line with this notion, the presence of TLOs and specific DC subsets within neoplastic lesions constitute a positive prognostic feature for patients with cancer (Dieu-Nosjean et al., 2008; Senovilla et al., 2012a).”
- Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer (2013, background): “Recently, ATP was shown to also mediate the recruitment and differentiation of myeloid DC to the tumor site following anthracycline treatment in mice.(99)”
- Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells (2014, background): “At the same time, however, removal of tumor-draining lymph nodes from mice bearing subcutaneous tumors did not alter response to CTX (Ma et al., 2013), tertiary lymphoid structures have been implicated in T cell activity in melanoma (Chen et al., 2013), and the presence of follicular helper T cells…”
- Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. (2013, background): “P2RY2-conveyed signals are required for the recruitment, persistence, and differentiation of DC precursors and neutrophils into the tumor bed (Elliott et al., 2009; Ma et al., 2013).”