Crystal Structure of the Extracellular Segment of Integrin αVβ3

By Jian-ping Xiong, T. Stehle, B. Diefenbach, Rong-guang Zhang, R. Dunker, D. Scott, A. Joachimiak, S. Goodman, M. Arnaout. Science, 2001

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Negative Staining and Image Classification – Powerful Tools in Modern Electron Microscopy (2004, background): “e and f: 3D reconstructions of an unliganded (e) and an Fn9-10-liganded α5β1 headpiece (f) with the fit atomic structures of the αV and β3 subunit (33) in red and blue, respectively, and of the Fn9-10 fragment (34) in white.”
Integrin Structure and Function (2010, background): “It took six additional years to solve the first complete extracellular domain of an integrin (avb3) (Xiong et al. 2001).”
The Immunological Synapse (2014, neutral): “[23–25].”
Demonstration of catch bonds between an integrin and its ligand (2009, positive): “S1), which is consistent with previous flow cytometric (Humphries, 2000), crystallographic (Xiong et al., 2001), and electron microscopic (Takagi et al., 2002; Zhu et al., 2008) studies.”