Hidden Killers: Human Fungal Infections

By Gordon D. Brown, David W. Denning, Neil A. R. Gow, S. Levitz, M. Netea, T. C. White. Science Translational Medicine, 2012

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Global and Multi-National Prevalence of Fungal Diseases—Estimate Precision (2017, background): “Pneumocystis jirovecii pneumonia is emerging as a leading cause of infection in HIV/AIDS patients [1].”
Global incidence and mortality of severe fungal disease. (2024, background): “The previous estimate of over 400 000 cases of pneumocystis pneumonia 4,13 is supported by the new estimate in this Review, with about 400 000 cases estimated in people with AIDS and 105 000 in other immuno-compromised patients (6·5 cases per 100 000 population).”
Candidalysin is a fungal peptide toxin critical for mucosal infection (2016, neutral): “For generation of the ece1Δ/Δ +ECE1 Δ184–279 strain, the CIp10-ECE1 was amplified with primers Pep3-F1 and Pep3-R1, digested with ClaI and re-ligated, yielding the CIp10+ECE1 Δ184–279 plasmid.”
FungiDB: An Integrated Bioinformatic Resource for Fungi and Oomycetes (2018, result): “[24] and compare transcriptomes of two strains of Cryptococcus neoforma s, a fungal organism causing fungal meningitis and high mortality rates in immunocompromised patients [25,26].”