Global and Multi-National Prevalence of Fungal Diseases—Estimate Precision

By F. Bongomin, S. Gago, R. Oladele, D. Denning. Journal of Fungi, 2017

2,544 citations recorded by the source corpus.

Fungal diseases kill more than 1.5 million and affect over a billion people. However, they are still a neglected topic by public health authorities even though most deaths from fungal diseases are avoidable. Serious fungal infections occur as a consequence of other health problems including asthma, AIDS, cancer, organ transplantation and corticosteroid therapies. Early accurate diagnosis allows prompt antifungal therapy; however this is often delayed or unavailable leading to death, serious chronic illness or blindness. Recent global estimates have found 3,000,000 cases of chronic pulmonary aspergillosis, ~223,100 cases of cryptococcal meningitis complicating HIV/AIDS, ~700,000 cases of invasive candidiasis, ~500,000 cases of Pneumocystis jirovecii pneumonia, ~250,000 cases of invasive aspergillosis, ~100,000 cases of disseminated histoplasmosis, over 10,000,000 cases of fungal asthma and ~1,000,000 cases of fungal keratitis occur annually. Since 2013, the Leading International Fungal Education (LIFE) portal has facilitated the estimation of the burden of serious fungal infections country by country for over 5.7 billion people (>80% of the world’s population). These studies have shown differences in the global burden between countries, within regions of the same country and between at risk populations. Here we interrogate the accuracy of these fungal infection burden estimates in the 43 published papers within the LIFE initiative.

Subfields: Cell Biology, Epidemiology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/a31bc4c8c2356520b0818d41b5c4a2e2091b6f32

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. M. Pfaller
2. D. Diekema

In Epidemiology

1. M. Pfaller
2. D. Diekema
3. Mariana Castanheira
4. Ronald N. Jones
5. J. Turnidge
6. J. Guinea

In Infectious Diseases

1. M. Pfaller
2. D. Diekema
3. Mariana Castanheira
4. J. Turnidge
5. Ronald N. Jones
6. J. Guinea

Citations in the corpus

• Global Epidemiology of Mucormycosis (2019, background): “After the inclusion of Indian data, the estimate of mucormycosis rose to 910,000 cases globally [23,24].”
• Twenty Years of the SENTRY Antifungal Surveillance Program: Results for Candida Species From 1997–2016 (2019, background): “The burden of invasive fungal infections (IFIs) for patients and health care systems is difficult to measure [2, 12]; however, it is well recognized that IFIs are associated with high morbidity and mortality rates and elevated health care costs.”