DNA replication in eukaryotic cells.

By S. Bell, Anindya Dutta. Annual Review of Biochemistry, 2002

2,255 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/91efbfffc5ea646fdf4b740936dbc2632a27357f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. W. G. Dunphy
2. A. Kumagai
3. Hiroyuki Araki
4. Debashish Chowdhury
5. Y. Kubota
6. Steven Henikoff
7. G. Zentner
8. J. Diffley

In Molecular Biology

1. A. Kumagai
2. W. G. Dunphy
3. George‐Lucian Moldovan
4. Hiroyuki Araki
5. Y. Kubota
6. Debashish Chowdhury
7. G. Zentner
8. Steven Henikoff

Citations in the corpus

• Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective (2012, background): “Thus, DdDPs alone cannot replicate the genome; together with DNA clamp and clamp loader, DNA helicase and primase, it forms a large multi-component complex machinery which is often referred to as the replisome [1585, 1586, 1587, 1588, 1589, 1590, 1591, 1592, 1593, 1594, 1595, 1596, 1597, 1598, 1599,”
• A vertebrate gene, ticrr, is an essential checkpoint and replication regulator. (2010, background): “To ensure that DNA replication occurs at the appropriate cell cycle stage, and that the DNA is copied once and only once, this process is divided into two temporally distinct steps (Bell and Dutta 2002; Sclafani and Holzen 2007).”
• Regulation of nucleosome dynamics by histone modifications (2013, positive): “Before DNA replication, chromatin regulates the accessibility of DNA to replication factors and modulates the firing and efficiency of replication origins, with a nucleosome-depleted, DNase-hypersensitive chromatin configuration conducive to proper origin firing 20 .”
• CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol (epsilon}, and GINS in budding yeast. (2010, background): “This loading also requires Cdt1 and Cdc6 (Bell and Dutta 2002; Schwob and Labib 2006; Sivaprasad et al. 2006; Walter and Araki 2006).”
• Concerted Loading of Mcm2-7 Double Hexamers Around DNA during DNA Replication Origin Licensing (2009, background): “A two-step mechanism underpins once-per-cell-cycle replication in eukaryotes (Bell and Dutta, 2002; Blow and Dutta, 2005; Diffley, 2004).”
• Mcm10 and And-1/CTF4 recruit DNA polymerase α to chromatin for initiation of DNA replication (2007, background): “In eukaryotic cells, DNA replication is dependent on the action of ORC, Cdc6, and Cdt1 to load the MCM2-7 complex onto replication origins, resulting in the formation of prereplicative complexes (pre-RC) (Bell and Dutta 2002).”
• Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS proteins (2010, background): “The loading of the MCMs on initiation sites requires the concerted contribution of several proteins, most notably the ORC complex, Cdc6, and Cdt1 (Bell and Dutta, 2002).”
• Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication (2010, background): “In eukaryotic cells, the duplication of the genome involves the strictly ordered assembly of various proteins onto regions of DNA that are destined to serve as origins of replication (Bell and Dutta, 2002; Mé ndez and Stillman, 2003; Sclafani and Holzen, 2007).”
• The N-Terminal Noncatalytic Region of Xenopus RecQ4 Is Required for Chromatin Binding of DNA Polymerase α in the Initiation of DNA Replication (2006, background): “The initiation of eukaryotic DNA replication involves the assembly of highly conserved replication proteins on replication origins (3, 15, 24).”