PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD

By B. Gross, M. Pawlak, P. Lefebvre, Bart Staels. Nature Reviews Endocrinology, 2017

685 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/91a5f4783b0d77bbf161cd18a417518c6422bf4b

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Citations in the corpus

• Trends in insulin resistance: insights into mechanisms and therapeutic strategy (2022, background): “Adipose tissue is a physiologic reservoir of fatty acids,(311) when the storage capacity is exceeded, the accumulation of heterotopic lipids leads to lipotoxicity, thereby promoting low-grade inflammation and IR in the liver.(312) Lipotoxicity impairs insulin signaling, induces oxidative damage, pro”