Diversity of mechanism-based pharmacodynamic models.

By D. Mager, E. Wyska, W. Jusko. Drug Metabolism And Disposition, 2003

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Pharmacokinetics and Pharmacodynamics of Systemically Administered Glucocorticoids (2005, methodology): “endogenous cortisol, blood lymphocesses are involved.[1,61,264] A fourth option is to cytes, osteocalcin[265]).”
In silico toxicology: computational methods for the prediction of chemical toxicity (2016, background): “Compartmental models consist of one or more compartments, and each compartment is usually represented by differential equations.(60,72,74) One-compartment models represent the whole body as a single compartment, assume rapid equilibrium of chemical concentration within the body after administration,”