mTOR signalling and cellular metabolism are mutual determinants in cancer

By Dirk Mossmann, Sujin Park, Michael N. Hall. Nature Reviews. Cancer, 2018

972 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/915da75822733838b6a8a1edf80c179b6da53cc7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Chu Tao
2. Tailin He
3. Mingjue Chen
4. Sheng Chen
5. Weiyuan Gong
6. Yiming Zhong
7. Minghao Qu
8. Xiaohao Wu

Citations in the corpus

• Osteoarthritis: pathogenic signaling pathways and therapeutic targets (2023, background): “Similar to mTORC1, mTORC2 also contains mTOR and mLST8, as well as the Rictor instead of DEPTOR, as its three main components, and mSin1 and Proctor1/2 as its regulatory subunits.(256) mTORC1 boosts protein synthesis by phosphorylation of S6K1 (p70S6 kinase) and 4EBP (eIF4E binding protein) and regu”