Metabolomics: a global biochemical approach to drug response and disease.

By Rima Kaddurah-Daouk, Bruce S. Kristal, Richard M. Weinshilboum. Annual Review of Pharmacology and Toxicology, 2008

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How researchers see this paper

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MetaboAnalyst: a web server for metabolomic data analysis and interpretation (2009, background): “While still a relatively new member of the ‘omics’ family, metabolomics is already ﬁnding applications in a wide variety of research ﬁelds including disease diagnosis (3), drug toxicity studies (4) and functional genomics (5).”
MetaboLights—an open-access general-purpose repository for metabolomics studies and associated meta-data (2012, background): “Metabolomics technologies yield many insights into basic biological research in areas such as systems biology and metabolic modeling (6), pharmaceutical research (7), nutrition (8) and toxicology (9).”
Predicting Network Activity from High Throughput Metabolomics (2013, methodology): “The technical platforms of metabolomics are mainly based on mass spectromety and nuclear magnetic resonance [4,7].”
Systems Pharmacology: Network Analysis to Identify Multiscale Mechanisms of Drug Action (2012, background): “Metabolomics focuses on measuring changes in a large number of metabolites simultaneously (27).”
Integrative Analysis of Multi-omics Data for Discovery and Functional Studies of Complex Human Diseases (2016, background): “Recent advances make untargeted studies (i.e. metabolome-wide association studies) now possible, as a powerful way to investigate complex biological questions (Jones et al., 2012; Kaddurah-Daouk et al., 2008; Patti et al., 2012).”