Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis

By Y. Yoshihara, Hiroyuki Nakamura, K. Obata, Harumoto Yamada, T. Hayakawa, K. Fujikawa, Y. Okada. Annals of the Rheumatic Diseases, 2000

602 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Matrix metalloproteinases: role in arthritis. (2006, background): “The collagenases (MMP-1, 8, -13), the gelatinases A and B (MMP-2 and -9 respectively), the stromelysins (MMP-3, -10, -11), the matrilysins (MMP-7, 26), and the MT-MMPs (membrane-type MMPs) are all expressed at low levels in normal joint tissue; however this expression is greatly increased in arthrit”
In vitro propagation of orchid ( Dendrobium nobile ) var. Emma white (2011, background): “Imbalances in the MMPs/TIMPs system (that is, lower levels of TIMPs and/or higher levels of MMPs) are also involved in the pathogenesis of several other diseases, including rheumatoid arthritis (Katrib et al., 2003; Yoshihara et al., 2000), which share several features with periodontitis, including ”
Articular cartilage and changes in Arthritis: Cell biology of osteoarthritis (2001, background): “To agonize the effects of MMPs, expression levels of inhibitors such as tissue inhibitor of metalloproteinases (TIMP)-1 are reduced in OA and rheumatoid arthritis [49,44,50], although the ratio of total”