Cytokine-induced sickness behavior.
By Keith W. Kelley, R. Bluthé, Robert Dantzer, Jian-hua Zhou, W. Shen, Rodney W. Johnson, S. Broussard. Brain, behavior, and immunity, 2003
725 citations recorded by the source corpus.
Subfields: Behavioral Neuroscience, Biological Psychiatry, Neurology
View Paper: https://www.semanticscholar.org/paper/908a10bffa59ea828627a186c42278cf17100de0
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In Behavioral Neuroscience
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Citations in the corpus
- Regulation of learning and memory by meningeal immunity: a key role for IL-4 (2010, background): “…depression, aging, and other somatic conditions that detrimentally affect cognitive function have been linked to an increase in the expression of proinflammatory cytokines and their receptors in different areas of the brain (Dantzer, 2001, 2008; Reichenberg et al., 2001; Kelley et al., 2003).”
- Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia (2008, background): “This inflammatory signal, in turn, induces CNS macrophages and microglia to produce the same cytokines [6], which target neuronal substrates and elicit a sickness behavior syndrome that is normally adaptive and beneficial to the host [1].”
- Mental fatigue: costs and benefits. (2008, background): “Pro-inflammatory cytokines are high in situations when energy is preferably allocated to immune function instead of to mechanisms of behavioural coping (Kelley et al., 2003).”
- Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system (2005, background): “Activated microglia produce inflammatory cytokines that are partially responsible for the progression of neurodegenerative disease (16) and for LPS-induced sickness behavior (35).”
- Interleukin-1 and neuronal injury (2005, background): “Many of these contribute to systemic host defence against diseases of the peripheral nervous system, as well as the CNS; host-defence responses include 'sickness behaviour', fever and the acute-phase respons”
- Candidate mechanisms for chemotherapy-induced cognitive changes (2007, background): “In addition, cytokine-induced sickness behaviour is associated with cognitive disturbance, fatigue and depressio”