Structural and Functional Diversity of Connexin Genes in the Mouse and Human Genome

By K. Willecke, Jürgen Eiberger, Joachim Degen, D. Eckardt, A. Romualdi, M. Güldenagel, U. Deutsch, G. Söhl. Biological chemistry, 2002

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How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Gap junctions and the connexin protein family. (2004, background): “The general genomic structure of connexin genes is relatively simple.”
The effects of connexin phosphorylation on gap junctional communication. (2004, background): “Deficient or improper gap junction function has recently been associated with a variety of diseases, including some forms of neuropathy, hereditary deafness, cataracts, skin disease, heart disease, and cancer (Willecke et al., 2002).”
Beyond the gap: functions of unpaired connexon channels (2003, background): “Detailed reviews of human connexin diseases and connexin-knockout mice have been published recentl”
Gap junctions: structure and function (Review) (2002, background): “…mouse knock-out models confirm that gap junctions play crucial roles in heart morphogenesis and cardiac conduction, but determining clear roles in cardiac development and function is hampered by the fact that cells express multiple connexin isoforms (Lo 2000; Lo et al. 1999, Willecke et al. 2002).”
Electrical coupling and neuronal synchronization in the Mammalian brain. (2004, neutral): “A substantial number (hundreds) of chanmammals (Willecke et al., 2002).”