Cholinergic suppression specific to intrinsic not afferent fiber synapses in rat piriform (olfactory) cortex.

By Michael E. Hasselmo, James M. Bower. 1992

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Martin Sarter
2. J. Bruno
3. B. Givens
4. Eric Schnell

Citations in the corpus

• Acetylcholine and Learning in a Cortical Associative Memory (1993, background): “Acetylcholine has postsynaptic effects on cortical neurons, causing increased spiking response to synaptic stimulation and current injection (ffrench-Mullen et af. 1983; Hasselmo and Bower 1992; Hasselmo and Barkai 1992).”
• Laminar selectivity of the cholinergic suppression of synaptic transmission in rat hippocampal region CA1: computational modeling and brain slice physiology (1994, methodology): “It is interesting to note that in these cases of selectivity of cholinergic suppression, the input to the proximal portion of pyramidal cell dendrites has been more strongly suppressed (Kahle and Cotman, 1989; Hasselmo and Bower, 1992; present results).”
• The role of acetylcholine in learning and memory. (2006, background): “In the piriform cortex, cholinergic modulation causes selective presynaptic inhibition of excitatory feedback potentials, whereas it has a much weaker effect on afferent synaptic potentials [21].”
• Switching between internal and external modes: A multiscale learning principle (2017, unknown): “…the relative strength of bottom-up input from the olfactory bulb Acetylcholine: An organic chemical that modulates and drives activity in diverse regions of central and peripheral nervous systems. versus top-down input from cortical sources (Hasselmo & Bower, 1992; Linster & Cleland, 2016).”
• Modes and Models of Forebrain Cholinergic Neuromodulation of Cognition (2010, background): “…of thalamic input through stimulation of nAChRs, while suppressing cortico-cortical or associational input through stimulation of mAChRs (Hasselmo and Bower, 1992; Hasselmo et al, 1992; Hasselmo and Schnell, 1994; Gil et al, 1997; Kimura and Baughman, 1997; Roberts et al, 2005; see…”
• Unraveling the attentional functions of cortical cholinergic inputs: interactions between signal-driven and cognitive modulation of signal detection. (2005, background): “Cortical ACh preferentially amplifies thalamocortical inputs while suppressing associational input Studies using cortical slices and assessing the effects of electrical stimulation have demonstrated that, in the presence of ACh or muscarinic agonists, inputs from other cortical areas were suppressed”