Systems survey of endocytosis by multiparametric image analysis

By C. Collinet, M. Stöter, C. Bradshaw, N. Samusik, J. Rink, D. Kenski, Bianca Habermann, F. Buchholz, R. Henschel, Matthias S. Mueller and 4 more. Nature, 2010

449 citations recorded by the source corpus.

Subfields: Biophysics, Cell Biology

View Paper: https://www.semanticscholar.org/paper/8dea9574848e27025d561c8ac0e4c187e2f366dc

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In Biophysics

1. Shantanu Singh
2. Anne E Carpenter
3. Daniel Gerlich
4. Christoph Sommer
5. Mark-Anthony Bray
6. Oren Z. Kraus
7. Juan C. Caicedo
8. Brendan J. Frey

In Cell Biology

1. M. von Zastrow
2. Sean D. Conner
3. Ari Helenius
4. Jatta Huotari
5. Pier Paolo Di Fiore
6. R. Juliano

Citations in the corpus

• Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling (2013, unknown): “Endosomal transport requires multiple heterotypic or homotypic endocytic fusion events with constantly changing vesicular milieu regulated by a diverse set of endosomal proteins and different cell signaling cascades 13,14 .”
• Endocytosis, Signaling, and Beyond (2014, background): “Indeed, cells tightly couple the number of EGFpositive endosomes, their size, and intracellular location to cargo concentration in the endosome (Collinet et al. 2010).”
• Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes (2016, methodology): “24| Centrifuge the plate (500 g at RT for 1 min) after adding stain solution, and ensure that there are no bubbles in the bottoms of the wells.”
• Endosome maturation (2011, background): “In addition, it is clear from recent data that location in the cytoplasm, measured as distance from the nucleus, is a key parameter that influences number, size, and cargo contents of endosomes consistent with the spatio-temporal progression of endosome maturation (Collinet et al, 2010).”
• Machine learning in cell biology – teaching computers to recognize phenotypes (2013, methodology): “…applied in diverse biological disciplines, such as high-content screening (Kittler et al., 2004; Lansing Taylor et al., 2007; Doil et al., 2009; Collinet et al., 2010; Fuchs et al., 2010; Neumann et al., 2010; Schmitz et al., 2010; Mercer et al., 2012), drug development (Perlman et al., 2004;…”
• PI5P4Kγ functions in DTX1-mediated Notch signaling (2018, background): “Thus, we cross-referenced the list of DTX1 substrates with genes implicated in receptor trafficking (30).”