Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster.

By S. Pletcher, S. Macdonald, R. Marguerie, U. Certa, S. Stearns, David B. Goldstein, Linda Partridge. Current Biology, 2002

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MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data (2003, unknown): “While GO has been used to annotate microarray data both by hand and by some software packages [9-11], there has been no automated way to use it for pathway-based analysis.”
Trade‐offs between longevity and pathogen resistance in Drosophila melanogaster are mediated by NFκB signaling (2006, background): “An inflammatory-like state has recently been described in old Drosophila (Pletcher et al., 2002; Seroude et al., 2002; Landis et al., 2004), suggesting that these signaling networks are ancient and that conserved mechanisms link immune activity, pathogen resistance, and aging.”
A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine (2005, background): “That this relates to energy metabolism was suggested by DNA microarray analyses that revealed the down-regulation with age of genes involved in metabolism, cell growth, and reproduction (180).”