Continuous single-cell imaging of blood generation from haemogenic endothelium

By Hanna M. Eilken, S. Nishikawa, T. Schroeder. Nature, 2009

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Hematopoietic stem cells derive directly from aortic endothelium during development (2010, unknown): “In vitro studies have also suggested that ESC derivatives can generate hematopoietic cells through hemogenic endothelial intermediates 3 , 4 , 6 .”
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A Novel Validation Algorithm Allows for Automated Cell Tracking and the Extraction of Biologically Meaningful Parameters (2011, background): “To date, cell tracking was regarded to be a powerful, but rather specialized method to investigate specific questions in developmental biology [5,6] or to find and explore rare events in cell culture [1,40].”