Lambda Interferon (IFN-λ), a Type III IFN, Is Induced by Viruses and IFNs and Displays Potent Antiviral Activity against Select Virus Infections In Vivo

By N. Ank, H. West, C. Bartholdy, K. Eriksson, A. Thomsen, S. Paludan. Journal of Virology, 2006

641 citations recorded by the source corpus.

Subfields: Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/8bf21f9ff50cf3a9a35e3c91bc16841699c80a71

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In Immunology

1. Bryan R. G. Williams
2. A. Sadler

Citations in the corpus

• IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy (2009, background): “This family of interleukins is expressed predominantly in antigen-presenting cells such as macrophages and dendritic cell”
• Interferon-inducible antiviral effectors (2008, background): “PKR is constitutively expressed in all tissues at a basal level and is upregulated by type I and type III IFN”
• IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo (2008, background): “IFN-λ expression has been shown to depend on the same triggers (viral infection, TLR ligands)”