Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles.
By E. Bermudez, J. Mangum, B. Wong, B. Asgharian, P. Hext, D. Warheit, J. Everitt. Toxicological Sciences, 2004
656 citations recorded by the source corpus.
Subfields: Environmental Engineering, Health, Toxicology and Mutagenesis
View Paper: https://www.semanticscholar.org/paper/8bd9f10b5b77fd5ed43aed0bf022377aed0f2797
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In Environmental Engineering
In Health, Toxicology and Mutagenesis
Citations in the corpus
- Toxicity of single walled carbon nanotubes to rainbow trout, (Oncorhynchus mykiss): respiratory toxicity, organ pathologies, and other physiological effects. (2007, background): “based nanomaterials such as carbon nanotubes (CNTs) or carbon nanospheres (“fullerenes”) (Lam et al., 2004; Oberd¨ orster, 2004; Cui et al., 2005), and the effects of metal or metal oxide nanoparticles ( Bermudez et al., 2004; Chen et al., 2006; Sayes et al., 2006).”
- Grey Goo on the Skin? Nanotechnology, Cosmetic and Sunscreen Safety (2007, background): “…(TiO2, carbon black or polystyrene) were reported to be somewhat enhanced—about 2 to 5 times (depending on the total particle surface) more than observed for the corresponding micro-sized particles—but did not lead to qualitatively new toxicities (Brown et al., 2001; Bermudez et al., 2002, 2004).”
- Alternative Antimicrobial Approach: Nano-Antimicrobial Materials (2015, background): “ROS generated from TiO 2 NM caused oxidative stress that resulted in early inflammatory responses in mice, rats, and hamsters [159].”
- Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy (2005, background): “These studies examined pulmonary toxicity associated with particulate matter deposition in the respiratory tract of target organisms [5-15].”
- Toxicity of titanium dioxide nanoparticles to rainbow trout (Oncorhynchus mykiss): gill injury, oxidative stress, and other physiological effects. (2007, methodology): “These concentrations of TiO2 NPs were selected after considering the concentrations used to produce epithelial injury and oxidative stress in rodents (Bermudez et al., 2004; Warheit et al., 2005, 2006), and the experiment was designed to allow for sub-lethal physiological effects over the exposure p”
- Occupational exposure to titanium dioxide (2011, methodology): “…volcanic ash [Cullen et al. 2002], (2) fine TiO 2 and BaSO 4 in a study of the particle surface area as dose metric [Tran et al. 1999], (3) fine TiO 2 in a multidose study [Bermudez et al. 2002], and (4) ultrafine TiO 2 in a multidose study 55NIOSH CIB 63 • Titanium Dioxide [Bermudez et al. 2004].”
- Titanium dioxide nanoparticles: a review of current toxicological data (2013, background): “A subchronic inhalation study comparing pulmonary responses to TiO2 NPs in several species was performed [129].”
- Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. (2007, methodology): “Concerning TiO2 toxicity, the analysis of bronchoalveolar lavage (BAL) fluid and histopathological changes for lung responses had been reported using bronchial instillation and inhalation methods in mice, rats, and hamsters ( Bermudez et al., 2002, 2004; Driscoll et al., 1990a,b; Henderson et al., ”
- Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay (2014, background): “In vivo toxicity studies have demonstrated that inhalation of TiO2 NPs causes pulmonary inflammation in rats and mice (Bermudez et al., 2004) and TiO2 NPs induce DNA damage and genetic instability in mice (Trouiller et al.”