Biomaterials based on chitin and chitosan in wound dressing applications.

By R. Jayakumar, M. Prabaharan, P. Kumar, S. Nair, H. Tamura. Biotechnology Advances, 2011

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Chitosan-based biomaterials for tissue engineering (2013, background): “wound dressing should be non-toxic and non-allergenic, allow gas exchanges, keep moist environment, protect the wound against microbial organisms and absorb wound exudates [80].”
Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a review. (2013, background): “Different synthetic and natural polymer-based biocompatible materials, as well as their mixtures or combinations and different processing methodologies, have been proposed and assayed both in vitro and in vivo for wound dressing (and DFU) applications [84–86].”
Preparation and application of chitin and its derivatives: a review (2014, background): “[100] with permission, copyright 2011, Elsevier 320 Iran Polym J (2014) 23:307–326”
Chitosan as a Wound Dressing Starting Material: Antimicrobial Properties and Mode of Action (2019, background): “Sponges • high porosity • thermal insulation • sustain a moist environment • absorb wound exudates • enhance tissue regeneration • mechanically weak • may provoke skin maceration • unsuitable for third-degree burn treatment or wounds with dry eschar [201,202]”
Chitin and Chitosan: Production and Application of Versatile Biomedical Nanomaterials (2016, background): “They are also antimicrobial and hydrating agents (2).”