Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.

By R. Ho, R. Tirona, B. Leake, H. Glaeser, Wooin Lee, C. J. Lemke, Yi Wang, R. Kim. Gastroenterology, 2006

640 citations recorded by the source corpus.

Subfields: Oncology, Pharmacology, Surgery

View Paper: https://www.semanticscholar.org/paper/89d95bdfbe7fa3cd7cbd14437015deab667b15bf

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In Oncology

1. M. Pasanen
2. Christoph Borner
3. M. Niemi
4. A. Kalliokoski
5. C. Klaassen
6. Lauren M. Aleksunes
7. P. Neuvonen

In Surgery

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2. H. Jaeschke

Citations in the corpus

• Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake (2011, background): “…activity of the c.521TϾC variant has been confirmed in later studies also with other substrates, such as rifampin, pravastatin, atorvastatin , rosuvastatin, atrasentan, and ezetimibe glucuronide (Tirona et al., 2003; Kameyama et al., 2005; Ho et al., 2006; Katz et al., 2006; Oswald et al., 2008).”
• Impact of OATP transporters on pharmacokinetics (2009, background): “Cyclosporine and gemfibrozil inhibit OATP2B1 in vitro (Ho et al., 2006b).”
• OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies (2012, neutral): “…et al. (2000); Kullak-Ublick et al. (2001) Rifampicin 2–13 Vavricka et al. (2002); Tirona et al. (2003) Ro 48-5033 60 Treiber et al. (2007) Rosuvastatin 9 Ho et al. (2006) S-8921G 1.93 Sakamoto et al. (2008) Saquinavir Hartkoorn et al. (2010) Simvastatin acid Pasanen et al. (2006) SN-38 Nozawa et…”
• Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME (2013, positive): “Like OATP1B1, OATP1B3 is also polymorphically expressed.”
• Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation (2010, background): “NTCP has a limited ability to transport pharmaceuticals (Ho et al., 2006b).”